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#21
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Talking with Ben
On Jan 22, 11:57�am, "Tom K" wrote:
You should stay in touch with the people who did the clinical study... if your stuff ever came back, the marketing company may be under obligation to give you the same drug for free. �Or they may do it voluntarily. --Tom They continue to follow my progress/status, with my permission. Formally, I was still part of the program for the year following the completion of the actual treatments. Naturally, they want to keep track of me to see for how long the benefits, if any, continue to work. I'm not sure I'd be eligible for futher treatments since nothing yet has been approved by the FDA. The U of V does continue to perform studies futher delineating the drug provided me. For those I may or may not be eligible in the future. I'd prefer not to find out! |
#22
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Talking with Ben
On 1/21/2009 9:59 PM PARNAMI scrawled with a big red tube of lipstick:
On Jan 21, 9:22�am, Susette wrote: On Jan 20, 10:16 pm, PARNAMI wrote: Hi Ben! It's good to see you're still alive and ticking! I've been curious about your whereabouts, naturally, thinking the worst. Glad I was wrong!! Stay well!! Mel WOW Mel �have not seen you on here in a coons age! Where have you been hiding? �Ben is alive and Kicking we going to do dinner... Susette Cruise Outlets and Travelwww.cruiseoutlets.com 856-853-9515 LOL....coons age? I've been here, reading, just about every night. I've just had nothing to say. In light of the poor treatment by airlines toward customers in recent years, pretty much, we've given up flying, meaning, in essence, cruising as well. If and when the airlines return to respecting their customers, we MAY begin traveling again, but, I'm not holding my breath. In the meantime, I'm spending my money with companies who actually APPRECIATE my business. OR, at least put up a good show of doing so. In other matters, three and a half years ago, I DID manage to come down with a small case of stage 4 metastasized melanoma of the lung. The lung was removed, I participated in a clinical trial of a vaccine, and, am happy to report, as of two days before Christmas, I remain CANCER FREE! So, no problems here!! I DO still have air miles with USAir..so I think I HAVE to check out a couple weeks on the Oasis..eventually. In all likelihood,that will be my last cruise/flight. So, as I said, not much about which to post. Is IS good, however, to contiune to see familar faces on the RTC. Hey guy, I may not have had the opportunity to sail with you.. Cancer Free that's awesome! I will say a special prayer to San Francisco die Assis. He's my best bud Saint along with Saint Tony. Thank your lucky stars that it wasn't squamous cell. -- ________ To email me, Edit "blog" from my email address. Brian M. Kochera "The poor dog is the firmest friend, the first to welcome the foremost to defend" - Lord Byron View My Web Page: http://home.earthlink.net/~brian1951 |
#23
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Talking with Ben
On 1/22/2009 1:28 AM Tom K scrawled with a big red tube of lipstick:
"PARNAMI" wrote in message ... On Jan 21, 11:04?pm, "Tom K" wrote: Glad to hear that. ?What was the drug? ?Do you remember? --Tom I'm not sure it has a name..yet..but here's the link: http://www.clinicaltrials.gov/ct/sho...118274?order=1 Thanks for the good thoughts. I'm really fine, show no ill effects, and do everything I did before...except without the coughing!! After a year on the vaccine, I now take no meds at all. I don't have a single brown bottle in the med cabinet....and have no need for o2. I really am "one lucky dude"!!! My timing, for once, just happend to be just right!! They don't give much info on the webpage... I was curious because I worked on a new biologic melanoma drug called ipilimumab for a while. Was wondering if that might have been the drug, but it's impossible to tell from what the webpage has. Cyclophophamide is an old drug. It's the peptide vaccine that I was curious about. With the new biologic products coming out, the whole world of drugs is changing leaps and bounds. Biologics are extremely difficult to make, and extremely expensive (some cost as much as $1000 just to make a single dose). But many of them work incredibly well, especially for things like cancer, rheumatoid arthritis, organ transplant rejection, lupus, etc.. Many of them are actually made from Chinese Hamster Ovary cells (CHO cells). It's a process almost like making beer in a big tank, only it uses the ovary cells (which multiply in the tank) instead of yeast. If you put the right materials into the tank the cells convert the materials into the biologic compound. It's a whole new world. --Tom Curious, why Chinese Hamsters? Why not American Hamsters? Do Chinese Hamsters have something going for them? I can't resist asking, is this just another case of Hamster Ovary outsourcing? But seriously, why Chinese Hamsters? -- ________ To email me, Edit "blog" from my email address. Brian M. Kochera "The poor dog is the firmest friend, the first to welcome the foremost to defend" - Lord Byron View My Web Page: http://home.earthlink.net/~brian1951 |
#24
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Talking with Ben
"Brian K" wrote in message m... Curious, why Chinese Hamsters? Why not American Hamsters? Do Chinese Hamsters have something going for them? I can't resist asking, is this just another case of Hamster Ovary outsourcing? But seriously, why Chinese Hamsters? Lot's of detail he http://en.wikipedia.org/wiki/Chinese_hamster_ovary_cell |
#25
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Talking with Ben
"PARNAMI" wrote in message ... In other matters, three and a half years ago, I DID manage to come down with a small case of stage 4 metastasized melanoma of the lung. The lung was removed, I participated in a clinical trial of a vaccine, and, am happy to report, as of two days before Christmas, I remain CANCER FREE! So, no problems here!! Great news, Parnami ! Good to see you posting here again. --Jean |
#26
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Talking with Ben
On 1/28/2009 11:11 AM Tom K scrawled with a big red tube of lipstick:
"Brian K" wrote in message m... Curious, why Chinese Hamsters? Why not American Hamsters? Do Chinese Hamsters have something going for them? I can't resist asking, is this just another case of Hamster Ovary outsourcing? But seriously, why Chinese Hamsters? Lot's of detail he http://en.wikipedia.org/wiki/Chinese_hamster_ovary_cell Very interesting but it isn't clear as to why Chinese Hamsters and not some other Hamster. Are there any biologists, or medical researchers lurking who could answer my question b/c? -- ________ To email me, Edit "blog" from my email address. Brian M. Kochera "The poor dog is the firmest friend, the first to welcome the foremost to defend" - Lord Byron View My Web Page: http://home.earthlink.net/~brian1951 |
#27
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Talking with Ben
Brian K wrote:
On 1/28/2009 11:11 AM Tom K scrawled with a big red tube of lipstick: "Brian K" wrote in message m... Curious, why Chinese Hamsters? Why not American Hamsters? Do Chinese Hamsters have something going for them? I can't resist asking, is this just another case of Hamster Ovary outsourcing? But seriously, why Chinese Hamsters? Lot's of detail he http://en.wikipedia.org/wiki/Chinese_hamster_ovary_cell Very interesting but it isn't clear as to why Chinese Hamsters and not some other Hamster. Are there any biologists, or medical researchers lurking who could answer my question b/c? The animal used has to have identical genetics as far as possible and need to be inbred for many generations to insure that. Chinese Hamsters appear to be the ones whose ovary cells were used first. They were introduced in the 1960s and are used in a cultured monolayer in culture flasks, but these type cells were first used back in 1919. Hamsters are used because they are so disease-free and breed so rapidly (they can have a new litter every month!) and because they are so friendly and easy to handle, they are a popular choice among scientists. They also have fewer chromosomes than some other species. They are often used for cardio-vascular research, as their cardio-vascular system is remarkably similar to that of the human. |
#28
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Talking with Ben
On 1/31/2009 12:05 PM Rosalie B. scrawled with a big red tube of lipstick:
Brian K wrote: On 1/28/2009 11:11 AM Tom K scrawled with a big red tube of lipstick: "Brian K" wrote in message m... Curious, why Chinese Hamsters? Why not American Hamsters? Do Chinese Hamsters have something going for them? I can't resist asking, is this just another case of Hamster Ovary outsourcing? But seriously, why Chinese Hamsters? Lot's of detail he http://en.wikipedia.org/wiki/Chinese_hamster_ovary_cell Very interesting but it isn't clear as to why Chinese Hamsters and not some other Hamster. Are there any biologists, or medical researchers lurking who could answer my question b/c? The animal used has to have identical genetics as far as possible and need to be inbred for many generations to insure that. Chinese Hamsters appear to be the ones whose ovary cells were used first. They were introduced in the 1960s and are used in a cultured monolayer in culture flasks, but these type cells were first used back in 1919. Hamsters are used because they are so disease-free and breed so rapidly (they can have a new litter every month!) and because they are so friendly and easy to handle, they are a popular choice among scientists. They also have fewer chromosomes than some other species. They are often used for cardio-vascular research, as their cardio-vascular system is remarkably similar to that of the human. Thanks Rosalie. I hope that they use tiny tiny instruments to extract the eggs. Too many animals get killed in the name of science. That's just my opinion. It's one of the reasons I tell my women friends about Aveda Cosmetics and Bath and Massage stuff. Aveda conducts no product experiments on animals. The bunny rabbits must be really happy about that. At Aveda nobody is going to stick eyeshadow in their eyes. Pigs won't have to wear skin clarifying cream and have lipstick put on their lips. It's good to know that at least one cosmetic line has the little and big critters in mind. -- ________ To email me, Edit "blog" from my email address. Brian M. Kochera "The poor dog is the firmest friend, the first to welcome the foremost to defend" - Lord Byron View My Web Page: http://home.earthlink.net/~brian1951 |
#29
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Talking with Ben
"Brian K" wrote in message m... Thanks Rosalie. I hope that they use tiny tiny instruments to extract the eggs. Too many animals get killed in the name of science. The cells aren't surgically extracted from an animal. They are a cell line, a cell culture. They grow in a large stainless steel vessel like yeast cells do. http://en.wikipedia.org/wiki/Cell_line Cell culture is the process by which prokaryotic or eukaryotic cells are grown under controlled conditions. In practice the term "cell culture" has come to refer to the culturing of cells derived from multicellular eukaryotes, especially animal cells. Animal cell culture became a common laboratory technique in the mid-1900's, but the concept of maintaining live cell lines separated from their original tissue source was discovered in the 19th century. An established snip cell line has acquired the ability to proliferate indefinitely either through random mutation or deliberate modification, such as artificial expression of the telomerase gene. There are numerous well established cell lines representative of particular cell types. |
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